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The Role of the Endocannabinoid System in Human Health


There’s a complex network of receptors, signaling molecules, and metabolic enzymes at play in the body that, despite having a significant influence on human health and well-being, most people don’t know about. The endocannabinoid system (ECS) – composed of cannabinoid receptors, endocannabinoids, and metabolic enzymes – serves an essential function in the human body: restoring homeostasis via various physiological and regulatory mechanisms.

Components of the ECS are present and vital in nearly every area of the human body. Thus, disruption of the ECS has a serious, negative impact on human health. The ECS is responsible for both basic homeostatic roles:

  • Relaxation
  • Metabolism
  • Sleep
  • Memory

And more complex functions:

  • Neuroplasticity
  • Modulation of embryonic development
  • Neuroprotection
  • Immunity and inflammation
  • Apoptosis
  • Carcinogenesis
  • Pain and emotional memory

Deemed the “endocannabinoid tone,” the proper functioning of the ECS depends on the density, functional status, and availability of endocannabinoids (eCBs), endogenous, tightly regulated, lipid signaling molecules synthesized as needed in neurons. These signaling molecules bind cannabinoid receptors (CBs) to inhibit the release of certain neurotransmitters.

Endocannabinoid tone is influenced by multiple external factors, such as physical activity, eating a well-balanced diet of macronutrients, micronutrients, and phytonutrients, and stress modification. Whatever the reason, endocannabinoid deficiency prevents the ECS from properly regulating homeostasis in the body, but supplementation with phytocannabinoids can resolve some of these issues.

Wholebody Solutions carries a new high quality product by Standard Process that supports the endocannabinoid system – Hemp Oil Complex

Hemp Oil Complex™ is a unique formulation of ingredients, combined to provide a 3-in-1 benefit for the whole body – supporting the endocannabinoid system, inflammation response resolution pathways, and endogenous anti-oxidant pathways.

  • Supports the endocannabinoid system*
  • Supports the body’s natural inflammatory response function*
  • Ingredients that provide antioxidant activity*
  • Non-genetically engineered hemp
  • Gluten-free
  • Combination of natural omega-3 fatty acids, including DHA, DPA and EPA
  • Calamari oil certified sustainable from the independent nonprofit group Friend of the Sea®

Learn more about this product here!

Call our office at 617-328-6300 to order or speak to one of our amazing nutritionists about what’s best for you.

Read the full Wholistic Matters article here

About Wholistic Matters:

Wholistic Matters is dedicated to advancing the latest insights and information available in nutrition therapy and clinical nutrition and present only the most balanced, credible and reliable clinical nutrition and science available. Partnering with some of the world’s most influential clinical investigators and institutions, this information is designed to keep users current in nutrition practices and improving health outcomes—because wholistic health really does matter.